Supermicro 4U GPU Server, NVIDIA H200, 8TB DDR5

• AI and deep-learning model training using NVIDIA HGX accelerator infrastructure
• Large language model training and natural language processing workloads
• High-performance computing for scientific and engineering applications
• Enterprise machine-learning development and model experimentation
• Research environments requiring high-density GPU compute
• Private AI infrastructure for controlled on-premises workloads
• Hybrid-cloud architectures retaining sensitive AI processing within the data center
• GPU-accelerated analytics and data-intensive computational workloads
• Scale-out AI and HPC clusters requiring high-speed GPU interconnects
• Data-center modernization and replacement projects for legacy accelerated-computing infrastructure

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• 4U rackmount Universal GPU server architecture
• Dual Socket E LGA-4677 processor platform
• Support for 4th and 5th Gen Intel Xeon Scalable processors
• Support for NVIDIA HGX H100 4-GPU and HGX H200 4-GPU configurations
• NVIDIA NVLink GPU-to-GPU interconnect
• PCIe 5.0 x16 CPU-to-GPU connectivity
• 32 DDR5 ECC DIMM slots
• Up to 8TB DDR5 memory at 5600MT/s
• Eight PCIe 5.0 x16 low-profile expansion slots
• Dual onboard 10GbE ports using Intel X710-AT2
• Six front hot-swap 2.5-inch NVMe/SATA drive bays
• Two M.2 NVMe/SATA boot-drive slots
• TPM 2.0 and Silicon Root of Trust with NIST 800-193 compliance
• IPMI 2.0 with virtual media and KVM-over-LAN
• Four redundant 3000W Titanium-level power supplies

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• Brand: Supermicro
• Part Number: SYS-421GU-TNXR
• Product Family: SuperServer 4U GPU
• Motherboard: Super X13DGU
• Form Factor: 4U Rackmount
• Processor Socket: Dual Socket E LGA-4677
• Supported Processor: 5th Gen Intel Xeon and 4th Gen Intel Xeon Scalable processors
• CPU Core Support: Up to 56 cores / 112 threads per CPU
• GPU Configuration: 4 onboard GPUs
• Supported GPU: NVIDIA SXM HGX H100 4-GPU 80GB or HGX H200 4-GPU 141GB
• CPU-GPU Interconnect: PCIe 5.0 x16
• GPU-GPU Interconnect: NVIDIA NVLink
• Memory Slots: 32 DIMM slots
• Maximum Memory: Up to 8TB 5600MT/s ECC DDR5
• Memory Voltage: 1.1V
• Network Connectivity: 2 RJ45 10GbE with Intel X710-AT2
• Expansion Slots: 8 PCIe 5.0 x16 LP slots
• Storage Bays: 6 front hot-swap 2.5-inch NVMe/SATA drive bays
• M.2: 2 M.2 NVMe/SATA slots
• Management: IPMI 2.0, KVM with dedicated LAN, SuperCloud Composer, Supermicro Server Manager, Supermicro Update Manager, Supermicro SuperDoctor 5
• Security: TPM 2.0, Silicon Root of Trust, NIST 800-193 compliant
• Video: 1 VGA port
• Power Supply: 4 x 3000W redundant Titanium-level power supplies
• Cooling: Up to 5 heavy-duty fans with optimal fan-speed control
• Optional Cooling: Direct-to-Chip cold plate
• Chassis Model: CSE-458GTS-R3K06P
• Chassis Dimensions: 449 x 175.6 x 833 mm
• Operating Temperature: 10°C to 35°C
• Operating Relative Humidity: 8% to 90%, non-condensing
• Lifecycle Status: Discontinued SKU; contact sales representative for alternatives

Why Choose This Product?

• SYS-421GU-TNXR combines four-GPU NVIDIA HGX support, dual Intel Xeon processing, up to 8TB DDR5 memory and eight PCIe 5.0 x16 expansion slots in a 4U platform. Its NVLink architecture, 10GbE connectivity and redundant Titanium-level power make it suited to demanding AI and HPC infrastructure. For replacement or expansion procurement, its discontinued status makes lifecycle availability and successor compatibility especially important.