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Supermicro 4U AMD EPYC GPU Server with MI250 OAM

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Supermicro AS-4124GQ-TNMI is a 4U AMD Universal GPU server designed for AI, deep learning and high-performance computing, combining dual AMD EPYC 7003 processors with four AMD Instinct MI250 OAM accelerators. Its 32 DDR4 DIMM slots support up to 8TB ECC memory, while PCIe 4.0 connectivity, AMD Infinity Fabric and flexible local storage support demanding accelerated workloads. The platform suits enterprise AI, HPC, scientific research, engineering and private-cloud environments where scalable GPU compute and high memory capacity are procurement priorities.

OVERVIEW

  • Supermicro AS-4124GQ-TNMI is a 4U AMD Universal GPU platform built for AI, deep-learning and high-performance computing workloads, using dual AMD EPYC 7003 processors and four AMD Instinct MI250 OAM accelerators. Its 32 DDR4 DIMM slots and support for up to 8TB ECC memory provide substantial capacity for memory-intensive workloads, while AMD Infinity Fabric supports high-speed GPU-to-GPU communication. The combination of four onboard accelerators, large memory capacity and PCIe 4.0 expansion distinguishes it from smaller GPU server platforms and supports scale-out AI and HPC infrastructure. It is well suited to enterprises, research institutions, engineering organizations and data-center operators planning GPU infrastructure expansion, replacement or modernization.

USE CASES

  • AI and deep-learning model training requiring dedicated GPU acceleration
  • High-performance computing for scientific, engineering and research workloads
  • Enterprise machine-learning infrastructure for model development and analytics
  • Research laboratories running simulations and computational workloads
  • Private-cloud GPU infrastructure for controlled enterprise AI workloads
  • Hybrid-cloud environments requiring on-premises accelerated computing
  • Large-scale data analytics combining high CPU memory capacity with GPU acceleration
  • Scale-out HPC clusters requiring GPU-to-GPU communication
  • AI development and testing environments for data science and engineering teams
  • Data-center modernization projects replacing conventional CPU-only compute infrastructure

KEY FEATURES

  • 4U AMD Universal GPU server architecture for enterprise AI and HPC
  • Dual AMD EPYC 7003 Series processor support
  • Four AMD Instinct MI250 OAM accelerators
  • AMD Infinity Fabric GPU-to-GPU interconnect
  • 1:1 GPU-to-NIC architecture for accelerator-focused networking
  • 32 DDR4 ECC DIMM slots across 8 memory channels
  • Up to 8TB ECC DDR4 RDIMM/LRDIMM memory
  • PCIe 4.0 x16 CPU-to-GPU connectivity
  • Eight PCIe 4.0 x16 expansion connections through PLX
  • Ten front hot-swap 2.5-inch NVMe/SAS/SATA drive bays
  • Dedicated 1GbE BMC management LAN
  • IPMI 2.0 with KVM-over-LAN management
  • TPM 2.0 and Silicon Root of Trust security features
  • Secure firmware update and automatic firmware recovery capabilities
  • Four redundant 3000W Titanium-level power supplies

TECHNICAL SPECIFICATIONS


  • Brand: Supermicro
  • Part Number: AS-4124GQ-TNMI
  • Product Family: A+ Server / Universal GPU System
  • Form Factor: 4U Rackmount
  • Motherboard: H12DGQ-NT6
  • Processor Socket: Dual Socket SP3
  • Supported Processor: AMD EPYC 7003 Series
  • Maximum CPU Configuration: Up to 128 Cores / 256 Threads
  • GPU: AMD Instinct MI250 OAM
  • GPU Configuration: 4 Onboard GPUs
  • GPU Interconnect: AMD Infinity Fabric
  • CPU-GPU Interconnect: PCIe 4.0 x16
  • Memory Slots: 32 DIMM Slots / 8 Channels
  • Memory Type: DDR4-3200 ECC RDIMM/LRDIMM
  • Maximum Memory: Up to 8TB
  • Expansion: 8 PCIe 4.0 x16 via PLX
  • Storage Bays: 10 Front Hot-Swap 2.5-inch NVMe/SAS/SATA Bays
  • Network Connectivity: AIOM
  • Management LAN: 1 RJ45 1GbE Dedicated BMC LAN
  • USB: 2 USB 3.0 Front Ports
  • Video: 1 VGA Port
  • Serial: 1 COM Port
  • Management: IPMI 2.0, KVM with Dedicated LAN, Supermicro Server Manager, Supermicro Power Manager, Supermicro Update Manager, SuperDoctor 5
  • Security: TPM 2.0, Silicon Root of Trust, NIST 800-193 Compliance
  • Power Supply: 4 x 3000W Redundant 2+2 Titanium-Level
  • Cooling: Up to 5 Hot-Swap 11.5K RPM Heavy-Duty Fans
  • Operating Temperature: 10°C to 35°C
  • Operating Relative Humidity: 8% to 90%, Non-Condensing
  • Chassis Model: CSE-458GTS-R3K06P

Why Choose This Product?

  • AS-4124GQ-TNMI combines four AMD Instinct MI250 OAM GPUs, dual AMD EPYC 7003 processors, up to 8TB ECC memory and PCIe 4.0 expansion in a 4U enterprise platform. AMD Infinity Fabric, 10 hot-swap storage bays and redundant Titanium-level power support demanding AI and HPC environments. It is a strong choice for organizations expanding GPU infrastructure, modernizing data centers or building scalable private AI and research clusters. Buyers should confirm the exact CPU, GPU, memory, networking and storage configuration before procurement.

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