HPE P19718-B21 ProLiant DL380 Gen10 12LFF CTO Rack Server

• Enterprise virtualization clusters running VMware, Hyper-V, or Proxmox.
• Software-defined storage and private cloud deployments.
• Centralized backup and disaster recovery repositories.
• Business-critical database hosting environments.
• File and application servers supporting distributed workforces.
• Hybrid cloud infrastructure and edge computing deployments.
• Data archiving and long-term retention platforms.
• ERP, CRM, and enterprise application hosting.
• High-capacity storage consolidation projects.
• Infrastructure modernization and legacy server replacement initiatives.

• 2U enterprise rack server architecture
• Part of the proven HPE ProLiant DL380 Gen10 family
• Supports up to two Intel Xeon Scalable processors
• 12 Large Form Factor (LFF) drive bay configuration
• Designed for compute and storage-intensive workloads
• 24 DIMM slots for memory scalability
• Supports HPE DDR4 SmartMemory technologies
• Flexible RAID controller options
• Modular networking architecture
• PCIe expansion capability for future growth
• Suitable for virtualization and cloud workloads
• Supports software-defined infrastructure strategies
• Redundant power supply support for availability
• Enterprise-grade reliability and workload resilience
• Optimized for infrastructure consolidation and operational efficiency

• Brand: HPE
• Product Model: HPE ProLiant DL380 Gen10
• SKU: P19718-B21
• Server Type: Configure-to-Order (CTO) Rack Server
• Form Factor: 2U Rack Mount
• Product Family: HPE ProLiant DL380 Gen10
• Drive Configuration: 12 LFF (Large Form Factor)
• Processor Support: Up to 2 Intel Xeon Scalable Processors
• Supported Xeon Families: Intel Xeon Scalable 3100, 4100, 5100, 6100, 8100 Series
• Processor Cores Supported: 4–28 cores per processor (depending on CPU selected)
• Chipset: Intel C621
• Memory Slots: 24 DIMM Slots
• Memory Type: HPE DDR4 SmartMemory RDIMM / LRDIMM
• Maximum Memory (LRDIMM): Up to 3.0 TB
• Maximum Memory (RDIMM): Up to 1.54 TB
• Intel Optane Persistent Memory Support: Up to 6.0 TB
• NVDIMM Support: Up to 192 GB
• Storage Controller Options: HPE Smart Array S100i, P408i-a, P816i-a, E208i-a (configuration dependent)
• Network Architecture: FlexibleLOM or supported network adapters
• Embedded Networking: No embedded networking
• PCIe Expansion: Three standard PCIe slots in primary riser
• Power Supply Support: Up to 2 HPE Flexible Slot Power Supplies
• Drive Cage Included: 12 LFF Drive Cage
• Deployment Type: Enterprise Data Center, Virtualization, Storage, Cloud Infrastructure

WHY CHOOSE THIS PRODUCT?

• Organizations choose the HPE ProLiant DL380 Gen10 P19718-B21 because it combines enterprise-class compute capability with a storage-focused 12LFF design that supports future growth without requiring immediate infrastructure replacement. The platform is particularly valuable for businesses seeking a single server architecture capable of supporting virtualization, backup, database, and storage-intensive workloads.
• Compared with smaller storage configurations within the DL380 Gen10 family, the 12LFF design delivers greater storage density for backup repositories, file services, and software-defined storage environments. At the same time, support for dual Intel Xeon Scalable processors, extensive memory expansion, modular networking, and flexible RAID options enables deployment across a wide range of enterprise workloads.
• Its compatibility with major operating systems, virtualization platforms, and hybrid cloud strategies helps reduce deployment complexity while protecting long-term infrastructure investments. For procurement teams, the platform offers strong lifecycle value, scalability, and upgrade flexibility, making it an effective choice for infrastructure refresh, consolidation, and modernization projects.