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Home Networking Servers & Storage HPE P05172-B21 ProLiant DL380 Gen10 Plus 8SFF NC Configure-to-Order Server

HPE P05172-B21 ProLiant DL380 Gen10 Plus 8SFF NC Configure-to-Order Server

Brand:
HPE

The HPE ProLiant DL380 Gen10 Plus 8SFF (P05172-B21) is a highly scalable 2U enterprise rack server designed for compute-intensive, virtualized, and business-critical workloads. Built on the HPE ProLiant DL380 Gen10 Plus platform, this configure-to-order (CTO) model supports 3rd Generation Intel Xeon Scalable processors, flexible storage expansion, advanced security features, and extensive PCIe expansion capabilities, making it a strong choice for data centers, hybrid cloud environments, virtualization clusters, database platforms, and enterprise application hosting.

OVERVIEW

  • The HPE ProLiant DL380 Gen10 Plus 8SFF (P05172-B21) is a 2U rack-mounted configure-to-order enterprise server engineered for organizations that require a balance of compute performance, storage flexibility, security, and future scalability. As part of the widely deployed DL380 Gen10 Plus family, this model provides support for dual 3rd Generation Intel Xeon Scalable processors, extensive memory capacity, and flexible storage architecture suitable for virtualization, database hosting, hybrid cloud infrastructure, and mission-critical applications.

USE CASES

  • Enterprise virtualization clusters running VMware, Hyper-V, or other hypervisors.
  • Database hosting for SQL, ERP, and business intelligence platforms.
  • Private cloud and hybrid cloud infrastructure deployments.
  • Business-critical application hosting and enterprise software environments.
  • Disaster recovery and business continuity infrastructure.
  • Software-defined storage and hyperconverged infrastructure projects.
  • Centralized file, print, and collaboration services.
  • Multi-tenant hosting and managed service provider environments.
  • Edge data center deployments requiring centralized management.
  • Infrastructure modernization and server consolidation initiatives.

KEY FEATURES

  • 2U enterprise rack server platform
  • Part of the HPE ProLiant DL380 Gen10 Plus family
  • 8 Small Form Factor (SFF) drive bay configuration
  • Configure-to-order deployment flexibility
  • Supports up to two 3rd Generation Intel Xeon Scalable processors
  • Up to 32 DIMM memory slots
  • Large memory scalability for virtualization and analytics workloads
  • Flexible storage controller options
  • Support for SAS, SATA, and NVMe storage configurations
  • Advanced HPE iLO 5 remote management
  • Silicon Root of Trust security architecture
  • TPM 2.0 and Secure Boot support
  • PCIe expansion for networking, storage, and accelerator cards
  • GPU support for specialized workloads
  • Redundant hot-plug power supply options
  • Hot-plug redundant cooling architecture
  • Designed for high availability environments
  • Supports enterprise operating systems and virtualization platforms
  • Suitable for hybrid cloud and software-defined infrastructure
  • Scalable lifecycle path for future upgrades and workload growth

TECHNICAL SPECIFICATIONS

  • Brand: HPE
  • Product Model: HPE ProLiant DL380 Gen10 Plus 8SFF NC CTO Server
  • SKU: P05172-B21
  • Product Family: HPE ProLiant DL380 Gen10 Plus
  • Form Factor: 2U Rack Server
  • Drive Configuration: 8 Small Form Factor (SFF) Bays
  • Processor Support: Up to 2 x 3rd Generation Intel Xeon Scalable Processors
  • Memory Slots: 32 DIMM Slots
  • Maximum Memory Capacity: Up to 4.0 TB DDR4 Memory
  • Storage Controller: Embedded Software RAID; Optional HPE Smart Array Controllers
  • PCIe Expansion: Three standard PCIe slots in primary riser
  • Networking: No embedded networking; OCP 3.0 and adapter-based networking options
  • Management: HPE iLO 5
  • Security Features: Silicon Root of Trust, TPM 2.0, Secure Boot
  • Internal Boot Options: UEFI Boot Support
  • Internal Storage Option: Optional M.2 Support
  • GPU Support: Supported with appropriate configuration
  • Power Options: Redundant HPE Flex Slot Power Supply Options
  • Operating System Support: Microsoft Windows Server, VMware, Red Hat Enterprise Linux, SUSE Linux Enterprise Server

WHY CHOOSE THIS PRODUCT?

  • Organizations select the HPE ProLiant DL380 Gen10 Plus 8SFF because it delivers a strong combination of performance, flexibility, and lifecycle value in a proven enterprise platform. The server supports extensive processor and memory scaling, enabling businesses to deploy it for virtualization, databases, cloud infrastructure, and business-critical applications without immediate hardware replacement.
  • The 8SFF design offers a practical balance between storage density and expansion capability, making it suitable for evolving infrastructure requirements. Combined with HPE iLO remote management, enterprise security features, and broad operating system compatibility, the platform helps reduce operational complexity while supporting long-term infrastructure modernization strategies.
  • For procurement teams, the CTO architecture provides investment protection by allowing the system to be configured for current needs and expanded as business requirements grow, improving overall return on investment and extending infrastructure lifecycle planning.

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