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Home Networking Servers & Storage HPE 878651-B21 ProLiant ML350 Gen10 Server | Xeon Gold 6150, 32GB RAM

HPE 878651-B21 ProLiant ML350 Gen10 Server | Xeon Gold 6150, 32GB RAM

Brand:
HPE

The HPE ProLiant ML350 Gen10 is a two-socket enterprise tower server platform built for virtualization, business applications, databases, file services and infrastructure workloads. This configuration pairs an Intel Xeon Gold 6150 processor with 32GB RAM and no installed HDDs, giving buyers a practical starting point for a customized storage deployment. Important SKU clarification: HPE identifies 878651-B21 specifically as the ML350 Gen10 Intel Xeon Gold 6150 processor kit, not as a complete server-system SKU.

OVERVIEW

  • The HPE ProLiant ML350 Gen10 is a scalable two-socket enterprise tower platform designed for virtualization, databases, business applications and infrastructure workloads, with 24 DIMM slots and extensive PCIe expansion. 
  • Compatibility: Intel Xeon Scalable, DDR4 RDIMM/LRDIMM and HPE ML350 Gen10-specific storage/expansion options. Model comparison: versus smaller ML-series platforms, ML350 Gen10 provides a broader dual-socket expansion foundation; ML350 Gen11 is the newer-generation alternative. 

USE CASES

  • Virtualization Host: Run multiple virtual machines for ERP, CRM, application, file, and infrastructure services while using the 18-core Xeon Gold 6150 as a capable compute foundation.
  • Database Server: Deploy relational databases and business data workloads with scalable DDR4 memory and flexible enterprise storage options.
  • Business Application Server: Support line-of-business applications where organizations need dedicated enterprise server hardware with room for future expansion.
  • File and Storage Server: Build a customized file server using compatible SAS, SATA, or NVMe storage based on required capacity, performance, and RAID strategy.
  • Private Cloud Infrastructure: Use the two-socket ML350 Gen10 platform as a customizable compute node for private-cloud and internal infrastructure environments.
  • Backup Server: Configure the no-HDD platform with suitable high-capacity drives to create a dedicated backup or data-retention server.
  • Development and Test Environment: Provide developers and IT teams with a configurable server for application testing, virtualization labs, staging, and QA workloads.
  • Network and Security Infrastructure: Add compatible PCIe networking or infrastructure adapters when additional connectivity or specialized processing is required.

KEY FEATURES

  • Intel Xeon Gold 6150 Processor: 18 cores, 36 threads, 2.7GHz base frequency, 24.75MB cache, and 165W TDP provide substantial compute capacity for virtualization, databases, and enterprise applications.
  • Two-Socket Server Architecture: Supports up to two compatible Intel Xeon Scalable processors, providing a practical upgrade path when future workloads require additional CPU resources.
  • 32GB DDR4 RAM Configuration: Provides an entry-level enterprise memory configuration for general workloads while leaving significant expansion capacity through the platform's 24 DIMM slots.
  • 24 DDR4 DIMM Slots: Supports HPE DDR4 SmartMemory RDIMM and LRDIMM options, allowing organizations to expand memory as application and virtualization requirements increase.
  • No HDD Configuration: Leaves storage selection open, allowing buyers to choose compatible SAS, SATA, or supported NVMe drives based on capacity, performance, endurance, and RAID requirements.
  • Flexible Storage Architecture: Supports multiple SFF and LFF drive configurations, making the platform adaptable for performance-focused, capacity-focused, or mixed storage deployments.
  • PCIe Gen3 Expansion: Provides expansion capability for compatible network adapters, storage controllers, accelerators, and other infrastructure cards.
  • HPE iLO 5 Management: Enables remote server monitoring, administration, and troubleshooting, helping IT teams reduce hands-on maintenance and improve operational efficiency.
  • Embedded Ethernet Connectivity: Applicable configurations include an HPE Ethernet 1Gb 369i 4-port adapter, providing baseline network connectivity without requiring an additional network card.

TECHNICAL SPECIFICATIONS

  • Brand: HPE
  • Product Family: HPE ProLiant ML350 Gen10
  • SKU / Part Number: 878651-B21
  • SKU Identification: HPE ML350 Gen10 Intel Xeon Gold 6150 Processor Kit
  • Processor: Intel Xeon Gold 6150
  • Processor Generation: 1st Gen Intel Xeon Scalable Processor
  • CPU Cores: 18
  • CPU Threads: 36
  • Base Frequency: 2.7 GHz
  • Maximum Turbo Frequency: Up to 3.7 GHz
  • Processor Cache: 24.75 MB L3
  • Processor TDP: 165 W
  • Processor Sockets: 2
  • Installed RAM: 32 GB
  • Memory Technology: DDR4 HPE SmartMemory
  • Supported Memory: RDIMM / LRDIMM
  • DIMM Slots: 24
  • Maximum Memory: Up to 3 TB LRDIMM, depending on configuration
  • Storage Included: No HDD
  • Supported Storage: SAS / SATA; supported NVMe configurations
  • Drive Form Factors: SFF / LFF, depending on chassis configuration
  • Maximum Drive Capacity: Up to 24 SFF or 12 LFF drives, depending on configuration
  • Expansion Interface: PCIe Gen3
  • PCIe Expansion: Up to 8 slots, configuration dependent
  • Networking: HPE Ethernet 1Gb 369i 4-port adapter on applicable configurations
  • Server Management: HPE iLO 5
  • Chipset Intel: C622
  • Form Factor: 4U Tower
  • Rack Deployment: Supported with appropriate HPE tower-to-rack conversion option
  • Storage Controller: Configuration dependent; Smart Array and software RAID options supported
  • Power Supply: Configuration dependent
  • Compatibility: ML350 Gen10-compatible CPU, DDR4 memory, drives, controllers, and expansion options

Why Choose This Product?

  • Strong multi-core processing: The Intel Xeon Gold 6150 provides 18 cores and 36 threads, making the platform suitable for virtualization, databases, business applications, and other parallel workloads.
  • Built for future expansion: The two-socket architecture provides an upgrade path to a second compatible processor when additional compute capacity is required.
  • Significant memory headroom: With 24 DDR4 DIMM slots, the ML350 Gen10 can be expanded well beyond the supplied 32GB configuration as virtualization and application workloads grow.
  • Storage tailored to your environment: The no-HDD configuration lets buyers select compatible SAS, SATA, or supported NVMe storage according to capacity, performance, endurance, and RAID requirements.
  • Flexible infrastructure deployment: The 4U tower design works well for server rooms and SMB environments, while the appropriate HPE rack conversion option supports future data-center deployment.
  • Remote management capability: HPE iLO 5 provides remote administration and monitoring capabilities, helping IT teams reduce physical intervention and simplify server operations.

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